Radiohalogenation of proteins: an overview of radionuclides, labeling methods, and reagents for conjugate labeling.

@article{Wilbur1992RadiohalogenationOP,
  title={Radiohalogenation of proteins: an overview of radionuclides, labeling methods, and reagents for conjugate labeling.},
  author={Daniel S Wilbur},
  journal={Bioconjugate chemistry},
  year={1992},
  volume={3 6},
  pages={433-70}
}
Direct labeling of proteins with radionuclides of iodine will continue to be the method of choice to answer questions addressed in many future studies. However, it seems likely that a increasing number of applications of radiohalogenated proteins will require, or benefit from, conjugate labeling. While many radiohalogen conjugates have been studied, a large proportion of them have only undergone preliminary studies to date, leaving a question of their overall utility. Phenolic conjugates give… CONTINUE READING