Radiofrequency Ablation: Inflammatory Changes in the Periablative Zone Can Induce Global Organ Effects, including Liver Regeneration.

@article{Rozenblum2015RadiofrequencyAI,
  title={Radiofrequency Ablation: Inflammatory Changes in the Periablative Zone Can Induce Global Organ Effects, including Liver Regeneration.},
  author={Nir Rozenblum and Evelyne Zeira and Baruch E. Bulvik and Svetlana Gourevitch and Hagit Yotvat and Eithan Galun and Shraga Nahum Goldberg},
  journal={Radiology},
  year={2015},
  volume={276 2},
  pages={
          416-25
        }
}
PURPOSE To determine the kinetics of innate immune and hepatic response to the coagulation necrosis area that remains in situ after radiofrequency (RF) ablation, the cytokine profile of this response, and its local and global effect on the whole organ in a small-animal model. MATERIALS AND METHODS A standardized RF ablation dose (70°C for 5 minutes) was used to ablate more than 7% of the liver in 91 C57BL6 mice (wild type) according to a protocol approved by the animal care committee. The… Expand
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