Radiochemical Evaluation and <i>In Vitro</i> Assessment of the Targeting Ability of a Novel <sup>99m</sup>Tc-HYNIC-RGD for U87MG Human Brain Cancer Cells.

Abstract

BACKGROUND Labeled RGD peptide that specifically targets ανβ3 integrin has great potential for the early diagnosis of malignant tumors.αvβ3 integrin receptors appear specifically more on the surface of glioblastoma (malignant glioma) cells rather than normal cells. OBJECTIVE The aim of this study was to identify a novel RGD that can be radiolabeled… (More)
DOI: 10.2174/1874471010666170706164016

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