Radiobiologic principles in radionuclide therapy.

  title={Radiobiologic principles in radionuclide therapy.},
  author={Amin I. Kassis and S. James Adelstein},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={46 Suppl 1},
Although the general radiobiologic principles underlying external beam therapy and radionuclide therapy are the same, there are significant differences in the radiobiologic effects observed in mammalian cells. External beam and brachytherapy emissions are composed of photons, whereas radiations of interest in radionuclide therapy are particulate. The special features that characterize the biologic effects consequent to the traversal of charged particles through mammalian cells are explored with… CONTINUE READING