Radioautographology general and special.

@article{Nagata2002RadioautographologyGA,
  title={Radioautographology general and special.},
  author={Tetsuji Nagata},
  journal={Progress in histochemistry and cytochemistry},
  year={2002},
  volume={37 2},
  pages={
          59-226
        }
}
  • T. Nagata
  • Published 2002
  • Biology
  • Progress in histochemistry and cytochemistry
Histochemistry, General and Special *
TLDR
The histochemical techniques have been well developed and systematized by the end of the 20 th century to demonstrate various components such as enzymes, proteins, nucleic acids, glucides, lipids, etc and should form a new field in medical sciences, which can be designated as "Special Histochemistry".
X-ray microanalysis of biological specimens by high voltage electron microscopy.
  • T. Nagata
  • Biology
    Progress in histochemistry and cytochemistry
  • 2004
Radioautographic studies on dna synthesis of the lungs of aging salamanders
TLDR
The DNA synthesis and morphological changes of the lungs of the salamanders, Hynobiusnebulosus, were studied by light microscopic radioautography and showed that the 3 types of cells proliferated in the early stages of development from 4 to 8 weeks and completed the development in the adult stages.
A microautoradiographic method for fresh-frozen sections to reveal the distribution of radionuclides at the cellular level in plants.
TLDR
The MAR method developed here is expected to provide distribution images for a variety of compounds and ions in plant tissue and was applicable for detecting cadmium (Cd) through vegetative rice stem tissue after 24 h of (109)Cd absorption.
Cell Aging of Mouse Gastrointestinal Tract Observed by Light and Electron Microscopic Radioautography
  • T. Nagata
  • Biology
    Gastroenterology research
  • 2014
TLDR
The incorporations and syntheses of various precursors for macromolecules such as DNA, RNA, proteins, glucides, lipids and others in various kinds of cells of various organs in the gastrointestinal tract such as the mouth, esophagus, stomach and intestines are reviewed.
CELL AGING OF ENDOCRINE SYSTEM AS OBSERVED BY LIGHT AND ELECTRON MICROSCOPIC RADIOAUTOGRAPHY
TLDR
The incorporations and syntheses of various precursors for macromolecules in various kinds of cells of various organ in endocrine system are reviewed referring many original papers already published from the authors' laboratory during these 50 years since the late 20C to the early 21C.
Drug localization and targeting with receptor microscopic autoradiography.
  • W. Stumpf
  • Biology
    Journal of pharmacological and toxicological methods
  • 2005
Cell Aging of the circulatory system as observed by Light and Electron Microscopic Radioautography
TLDR
The author and associates of this article have been studying the latter changes from the viewpoint of the cell nutrients, the precursors for the macromolecular synthesis such as DNA, RNA, proteins, glucides and lipids, which are incorporated and synthesized into various cells of individual animals.
Electron Microscopic Radioautographic Study on the Protein Synthesis in the Pancreas of Aging Mice With Special Reference to Mitochondria
  • T. Nagata
  • Biology, Medicine
    Gastroenterology research
  • 2011
TLDR
The number of mitochondria, the number of labeled mitochondria and the labeling indices showing protein synthesis at various ages increased from embryonic day 19 to postnatal newborn day 1, 3, 7, 14, to young adult month 1, and 2, reaching the maxima, then decreased at old adult month 6 and senile year 1 to 2, indicating the aging changes.
Light Microscopic Radioautographic Study on Radiosulfate Incorporation into the Tracheal Cartilage of Aging Mice
TLDR
It is concluded that the radiosulfate was incorporated into sulfated complex carbohydrate in the cartilage matrices and the pattern of incorporation in the tracheae decreased with the aging of animals.
...
...

References

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Techniques of radioautography for medical and biological research.
  • T. Nagata
  • Biology
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
  • 1998
Standard techniques for radioautography used in biological and medical research can be classified into three categories, i.e., macroscopic radioautography, light microscopic radioautography and
On the terminology of radioautography vs. autoradiography.
  • T. Nagata
  • Medicine
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
  • 1996
TLDR
It is the author's opinion that the Journal of Histochemistry and Cytochemistry should accept both radioautography and autoradiography, according to the authors’ preferences, and it is hoped that in the future the Editor accepts both terms as requested by authors.
Techniques and application of microscopic radioautography.
  • T. Nagata
  • Biology, Chemistry
    Histology and histopathology
  • 1997
TLDR
These procedures are expected to be applied for various inorganic and organic compounds in living organisms to elucidate the sites of their incorporation, synthesis and discharge.
Radioautographic study on the intracellular localization of a hypolipidemic agent, bezafibrate, a peroxisome proliferator, in cultured rat hepatocytes.
TLDR
It is demonstrated that theperoxisome proliferator acts on the endoplasmic reticulum of hepatocytes to proliferate peroxisomes.
Radioautographic study on the localization of an anti-allergic agent, tranilast, in the rat liver.
TLDR
It was concluded that the localization of radioautographic silver grains was associated with Tranilast uptake of hepatocytes in each hepatic lobular compartment and that the metabolic process from uptake to excretion of Traninilast took part in the hepatocyte in each liver compartment.
ELECTRON MICROSCOPIC RADIOAUTOGRAPHY WITH CRYO-FIXATION AND DRY-MOUNTING PROCEDURE
TLDR
Various soluble compounds, including nucleotide precursor, proteins, lipids, polysaccharides precursors, hormones, drugs and inorganic compounds, are generally localized diffusely in both the nucleus and the cytoplasm of various cells examined.
QUANTITATIVE ELECTRON MICROSCOPE RADIOAUTOGRAPHY OF INTRAMITOCHONDRIAL NUCLEIC ACID SYNTHESIS
TLDR
The present author has been studying the nucleic acid synthesis in the mitochondria of various vertebrate cells in vitro by means of electron microscope radioautography, and this paper deals with the stochastical analyses on the problems of quantitative techniques.
Histochemistry: Theoretical and Applied
TLDR
The new Pearse bids fair to become the leader, even amongst so notable a collection of books devoted entirely or largely to histochemical techniques.
A radioautographic study on the incorporation of 14C-bupranolol (beta-blocking agent) into the rabbit eye
TLDR
Localization of instilled 14C-bupranolol was studied in the rabbit eye by means of light microscopic radioautography, and results suggest that bupranolol plays a role in the control of aqueous production in the ciliary processes.
[Histochemistry of the organs--application of histochemistry to anatomy].
  • T. Nagata
  • Medicine
    Kaibogaku zasshi. Journal of anatomy
  • 1995
TLDR
The author and coworkers made efforts to apply these techniques to various organ systems of humans and animals since the 1970s to the present time and collected data from all the organs including the aging process from embryos, neonates, sucklings, weanlings, adults and to senescence.
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