Radioautographic Localization of the Increased Synthesis of Phosphatidylinositol in Response to Pancreozymin or Acetylcholine in Guinea Pig Pancreas Slices


A technique is described for measuring the incorporation of myo-inositol-2-(3)H into the lipid of various regions of the guinea pig pancreatic acinar cell by radioautography. Stimulation of enzyme secretion with either pancreozymin or acetylcholine was associated with increased graining in both the basophilic cytoplasm and the nonbasophilic cytoplasm… (More)


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