Radioactive Isotopes in Clinical Medicine and Research

  title={Radioactive Isotopes in Clinical Medicine and Research},
  author={D. Goodwin},
  booktitle={Advances in Pharmacological Sciences},
  • D. Goodwin
  • Published in
    Advances in Pharmacological…
  • IN1RODUCTION: Colonic transit is accelerated in lactulose (LL) induced diarrhea; it is not clear whether this is simply due to an osmotic effect or is influenced by bacterial metabolism of LL. AIMs: To compare colonic transit induced by LL with that produced by PEG, an osmotically active, non metabolizable solute ("pure osmotic diarrhea"). MErnODS: To cause similar severity of diarrhea (J Clin Invest 1989, 84: 1 056) 10 healthy volunteers (24±6 yrs, 3F, 1M) ingested 99 g/d LL and 7 subjects (26… CONTINUE READING
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