Radical treatment of non-small-cell lung cancer patients with synchronous oligometastases: long-term results of a prospective phase II trial (Nct01282450).

@article{Ruysscher2012RadicalTO,
  title={Radical treatment of non-small-cell lung cancer patients with synchronous oligometastases: long-term results of a prospective phase II trial (Nct01282450).},
  author={Dirk K. M. De Ruysscher and Rinus Wanders and Angela A W van Baardwijk and A. M. Dingemans and Bart H Reymen and Ruud M. A. Houben and Gerben Bootsma and Cordula C. M. Pitz and Linda van Eijsden and Wiel H. Geraedts and Brigitta G. Baumert and Philippe Lambin},
  journal={Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer},
  year={2012},
  volume={7 10},
  pages={1547-55}
}
BACKGROUND Stage IV non-small-cell lung cancer (NSCLC) patients with oligometastases (< 5 metastatic lesions) may experience long-term survival when all macroscopic tumor sites are treated radically, but no prospective data on NSCLCs with synchronous oligometastases are available. METHODS A prospective single-arm phase II trial was conducted. The main inclusion criteria were pathologically proven NSCLC stage IV with less than five metastases at primary diagnosis, amendable for radical local… CONTINUE READING