Radical retropubic prostatectomy: A review of outcomes and side-effects

  title={Radical retropubic prostatectomy: A review of outcomes and side-effects},
  author={Jonas Hugosson and Johan Stranne and Sigrid V. Carlsson},
  journal={Acta Oncologica},
  pages={92 - 97}
Abstract Background. Radical prostatectomy (RP) is worldwide probably the most common procedure to treat localized prostate cancer (PC). Due to a more widespread use of Prostate-Specific Antigen (PSA) testing, patients operated today are often younger and have organ confined disease justifying a more preservative surgery. At the same time, surgical technique has improved resulting in lower risk of permanent side-effects. This paper aims to give an overview of results from modern surgery… 

The Diagnosis and Treatments of Inguinal Hernia after Radical Prostatectomy

There is no one efficient and precise method influenced this procedure occurred and recent studies about IH after RP through different approaches are reviewed to evaluate the development of this procedure.

Radical prostatectomy versus deferred treatment for localised prostate cancer.

Assessment of effects of RP compared with deferred treatment for clinically localised prostate cancer found that radical prostatectomy versus watchful waiting RP probably reduces the risk of death from any cause and probably reducesThe risk of developing metastatic disease.

Inguinal hernia developed after radical retropubic surgery for prostate cancer

Inguinal hernia following radical retropubic surgery for prostate cancer was predominantly right side and indirect type with statistic significance compared to hernias without previous radical prostatectomy.

The Quadrella: a novel approach to analyzing optimal outcomes after permanent seed prostate brachytherapy.

Does a surgeon's annual radical prostatectomy volume predict the risk of positive surgical margins and urinary incontinence at one-year follow-up? - Findings from a prospective national study

Assessment of the prevalence of positive surgical margins (PSM) and urinary incontinence (UI) in relation to surgeons' annual radical prostatectomy (RP) volume and preoperative counselling should take into account the relationship between surgeon's annual RP volume and PSM rate and the current knowledge about UI and ULP.

Local Administration of Tranexamic Acid During Prostatectomy Surgery: Effects on Reducing the Amount of Bleeding

The present study showed that local administration of TRA significantly reduces bleeding after prostatectomy surgery and is effective in preventing postoperative hemoglobin decrease.

Dose to the penile bulb and individual patient anatomy are predictive of erectile dysfunction in men treated with 125I low dose rate brachytherapy for localized prostate cancer

The prostate position, especially the apex location varied significantly between potent and impotent patients and 3yED was significantly associated with close position of the prostate apex to PB, which could allow for the development of better strategies to prevent ED.

Results of a randomized trial of treatment modalities in patients with low or early-intermediate risk prostate cancer (PREFERE trial)

The randomized PREFERE trial aimed to assess noninferiority of active surveillance, external-beam radiotherapy, EBRT, or brachytherapy by permanent seed implantation against radical prostatectomy for patients with low to early-intermediate risk prostate cancer.

Physical activity before radical prostatectomy reduces sick leave after surgery - results from a prospective, non-randomized controlled clinical trial (LAPPRO)

In the study of med operated with radical prostatectomy, a high level of physical activity preoperatively was associated with reduced need for sick leave after radical prostateCTomy compared to men with lower physical activity.



Baseline potency in candidates for bilateral nerve-sparing radical retropubic prostatectomy.

Comparative effectiveness of minimally invasive vs open radical prostatectomy.

Men undergoing MIRP vs RRP experienced shorter length of stay, fewer respiratory and miscellaneous surgical complications and strictures, and similar postoperative use of additional cancer therapies but experienced more genitourinary complications, incontinence, and erectile dysfunction.

Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial.

Radical prostatectomy reduces prostate cancer mortality and risk of metastases with little or no further increase in benefit 10 or more years after surgery.

Incontinence and Erectile Dysfunction Following Radical Prostatectomy: A Review

The incidence of incontinence and erectile dysfunction is higher after radical prostatectomy when compared to the incidence observed when other therapies for localized prostate cancer are applied, but general and cancer-specific health-related quality of life is not being affected.

Erectile Dysfunction Following Radical Retropubic Prostatectomy

The epidemiology, pathophysiology and treatment options available for ED following radical prostatectomy are discussed and initial attempts to promote the earlier recovery of erectile function appear to be promising.

Radical prostatectomy versus watchful waiting for prostate cancer.

The existing trials provide insufficient evidence to allow confident statements to be made about the relative beneficial and harmful effects of RP and WW for patients with localised prostate cancer, and the results of ongoing trials should help to inform treatment decisions for men with screen-detected localisation prostate cancer.

Radical Prostatectomy: Status and Opportunities for Improving Outcomes

  • H. Lepor
  • Medicine
    Cancer investigation
  • 2004
The next major advance in the surgical technique of radical prostatectomy was the description of the nerve sparing and anatomic radical retropubic prostatectome by Walsh, which decreased intraoperative complications and greatly increased the probability that men would maintain their potency.