Radical hypofractionated accelerated radiotherapy with cytoprotection for invasive bladder cancer.

@article{Koukourakis2007RadicalHA,
  title={Radical hypofractionated accelerated radiotherapy with cytoprotection for invasive bladder cancer.},
  author={Michael I. Koukourakis and Christos Tsolos and Stavros Touloupidis},
  journal={Urology},
  year={2007},
  volume={69 2},
  pages={245-50}
}
OBJECTIVES To report a series of patients with bladder cancer treated with hypofractionated accelerated radiotherapy with amifostine cytoprotection, with or without concurrent liposomal doxorubicin. Radiochemotherapy has been shown to be an effective alternative to cystectomy. METHODS A total of 38 patients with invasive bladder cancer were treated with 15 consecutive fractions of 3.4 Gy (2.7 Gy to the pelvis and a 0.7-Gy concomitant boost to the bladder; total biologic dose 66 to 72 Gy in 19… CONTINUE READING