Radical Cation Cyclopropanations via Chromium Photooxidative Catalysis.


The chromium photocatalyzed cyclopropanation of diazo reagents with electron-rich alkenes is described. The transformation occurs under mild conditions and features specific distinctions from traditional diazo-based cyclopropanations (e.g., avoiding β-hydride elimination, chemoselectivity considerations, etc.). The reaction appears to work most effectively using chromium catalysis, and a number of decorated cyclopropanes can be accessed in generally good yields.

DOI: 10.1021/acs.orglett.7b01095

Cite this paper

@article{Sarabia2017RadicalCC, title={Radical Cation Cyclopropanations via Chromium Photooxidative Catalysis.}, author={Francisco Sarabia and Eric M Ferreira}, journal={Organic letters}, year={2017}, volume={19 11}, pages={2865-2868} }