Radiation therapy of acromegaly.

  title={Radiation therapy of acromegaly.},
  author={Richard T Eastman and Phil Gorden and Eli J. Glatstein and John Kyle Roth},
  journal={Endocrinology and metabolism clinics of North America},
  volume={21 3},
Conventional megavoltage irradiation of GH-secreting tumors has predictable effects on tumor mass, GH, and pituitary function. 1. Further growth of the tumor is prevented in more than 99% of patients, with only a fraction of a percent of patients requiring subsequent surgery for tumor mass effects. 2. GH falls predictably with time. By 2 years GH falls by about 50% from the baseline level, and by 5 years by about 75% from the baseline level. The initial GH elevation and the size and erosive… CONTINUE READING


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