Radiation therapy for diabetes insipidus caused by Langerhans cell histiocytosis.

  title={Radiation therapy for diabetes insipidus caused by Langerhans cell histiocytosis.},
  author={K J Minehan and Michael G Chen and Deborah K Zimmerman and John Q. Su and Thomas Vail Colby and Edward G. Shaw},
  journal={International journal of radiation oncology, biology, physics},
  volume={23 3},
Hypothalamic-pituitary radiation therapy has been the standard treatment for the diabetes insipidus of Langerhans cell histiocytosis. The goal of this study was to assess the role of radiation therapy in Langerhans cell histiocytosis-associated diabetes insipidus and to compare the results with nonirradiated controls. Forty-seven patients with pathologically confirmed Langerhans cell histiocytosis were diagnosed with diabetes insipidus between 1950 and 1989 and were treated at the Mayo Clinic… CONTINUE READING


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