Radiation therapy and malignant degeneration of benign supratentorial gangliogliomas.


OBJECTIVE Gangliogliomas are indolent tumors comprised of neoplastic glial and neuronal cells. Benign lesions tend to be associated with long survival unless the tumor degenerates to a histologically malignant form. This study reviews four cases of histologically proven benign ganglioglioma that later demonstrated malignant features within the glial… (More)