Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes

@inproceedings{Yin2015RadiationQO,
  title={Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes},
  author={Xiaoming Yin and Wenqian Tian and Longxiao Wang and Jingdong Wang and Shuyu Zhang and Jianping Cao and Hongying Yang},
  booktitle={Scientific reports},
  year={2015}
}
Traditional radiation biology states that radiation causes damage only in cells traversed by ionizing radiation. But radiation-induced bystander effect (RIBE), which refers to the biological responses in unirradiated cells when the neighboring cells are exposed to radiation, challenged this old dogma and has become a new paradigm of this field. By nature, RIBEs are the consequences of intercellular communication between irradiated and unirradiated cells. However, there are still some important… CONTINUE READING
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