Radiation injury and the protein C pathway.

  title={Radiation injury and the protein C pathway.},
  author={Martin Hauer-Jensen and Louis M. Fink and Junru R Wang},
  journal={Critical care medicine},
  volume={32 5 Suppl},
OBJECTIVE To summarize current knowledge regarding the role of the thrombomodulin (TM)-protein C system in acute and chronic radiation responses in normal tissues. DATA SOURCE Studies published in the biomedical literature during the past three decades and cited in PubMed and unpublished clinical and laboratory data from our own research program. STUDY SUMMARY: The risk of injury to normal tissues limits the cancer cure rates that can be achieved with radiation therapy. Microvascular injury… CONTINUE READING

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