Radiation-induced xerostomia in cancer patients. Effect on salivary and serum electrolytes.

@article{Dreizen1976RadiationinducedXI,
  title={Radiation-induced xerostomia in cancer patients. Effect on salivary and serum electrolytes.},
  author={S Dreizen and Lyle R. Brown and S F Handler and Barnet M. Levy},
  journal={Cancer},
  year={1976},
  volume={38 1},
  pages={273-8}
}
Saliva and serum electrolyte concentrations were monitored in 30 patients given a course of xerostomia-producing cancer radiotherapy. The mean flow rate of stimulated whole saliva decreased 83.3% during a 6-week treatment period. The striking reduction in saliva output was accompanied by significant increases in saliva Na+, Cl-, Ca++, Mg++ and Prot.- concentrations and by a decrease in saliva HCO3- content. The xerostomic saliva was more concentrated and had a greater salinity than the… CONTINUE READING