Radiation-induced meningioma following prophylactic radiotherapy for acute lymphoblastic leukemia in childhood.

@article{Kawahara2007RadiationinducedMF,
  title={Radiation-induced meningioma following prophylactic radiotherapy for acute lymphoblastic leukemia in childhood.},
  author={Ichiro Kawahara and Kenta Masui and Nobutaka Horie and Takayuki Matsuo and Naoki Kitagawa and Keisuke Tsutsumi and Izumi Nagata and Minoru Morikawa and Tomayoshi Hayashi},
  journal={Pediatric neurosurgery},
  year={2007},
  volume={43 1},
  pages={36-41}
}
BACKGROUND Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Although it was considered to be a poor prognostic disease, modern treatment protocols (aggressive chemotherapy and prophylactic cranial irradiation) have resulted in dramatically improved survival rates. In a group of low-risk ALL patients, the 5-year survival rate is estimated to be 85%. However, ALL patients who undergo this treatment are at risk of developing secondary neoplasms related to treatment… CONTINUE READING