Radiation-induced mammary carcinogenesis in rodent models: what's different from chemical carcinogenesis?

@article{Imaoka2009RadiationinducedMC,
  title={Radiation-induced mammary carcinogenesis in rodent models: what's different from chemical carcinogenesis?},
  author={Tatsuhiko Imaoka and Mayumi Nishimura and Daisuke Iizuka and Kazuhiro Daino and Takashi Takabatake and Mieko Okamoto and Shizuko Kakinuma and Yoshiya Shimada},
  journal={Journal of radiation research},
  year={2009},
  volume={50 4},
  pages={281-93}
}
Ionizing radiation is one of a few well-characterized etiologic factors of human breast cancer. Laboratory rodents serve as useful experimental models for investigating dose responses and mechanisms of cancer development. Using these models, a lot of information has been accumulated about mammary gland cancer, which can be induced by both chemical carcinogens and radiation. In this review, we first list some experimental rodent models of breast cancer induction. We then focus on several topics… CONTINUE READING

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