Radiation-induced heart disease: A practical guide to diagnosis and management
@article{Donnellan2016RadiationinducedHD, title={Radiation-induced heart disease: A practical guide to diagnosis and management}, author={Eoin Donnellan and Dermot M. Phelan and Cian P McCarthy and Patrick Collier and Milind Y. Desai and Brian P. Griffin}, journal={Cleveland Clinic Journal of Medicine}, year={2016}, volume={83}, pages={914 - 922} }
Radiation-induced heart disease (RIHD) is a recognized late sequela of chest radiotherapy for conditions such as breast cancer and lymphoma and can involve any cardiac structure. Consensus guidelines from the European Association of Cardiovascular Imaging and the American Society of Echocardiography stress the importance of regular screening for the cardiac effects of radiotherapy. However, a gulf remains between these guidelines and clinical practice. Unfortunately, radiotherapy for breast…
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References
SHOWING 1-10 OF 67 REFERENCES
Radiation-Induced Cardiovascular Disease
- MedicineCurrent Treatment Options in Cardiovascular Medicine
- 2013
The pathophysiological features, clinical presentations, and current recommendations for screening and prevention of the wide spectrum of radiation induced cardiovascular disease will be summarized.
Radiation-associated cardiovascular disease: manifestations and management.
- MedicineSeminars in radiation oncology
- 2003
Radiation dose-volume effects in the heart.
- MedicineInternational journal of radiation oncology, biology, physics
- 2010
Heart transplantation for radiation-associated end-stage heart failure
- MedicineTransplant international : official journal of the European Society for Organ Transplantation
- 2000
Four cases of heart transplantation for end-stage heart failure induced by mediastinal radiation therapy are reported, with all four patients currently surviving a mean of 48 months after transplantation.
Expert consensus for multi-modality imaging evaluation of cardiovascular complications of radiotherapy in adults: a report from the European Association of Cardiovascular Imaging and the American Society of Echocardiography.
- MedicineJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
- 2013
Minimizing Cardiac Risks With Contemporary Radiation Therapy for Hodgkin Lymphoma.
- MedicineJournal of clinical oncology : official journal of the American Society of Clinical Oncology
- 2016
This study is the first to demonstrate a linear, no-threshold relationship betweenmean heart dose and development of coronary heart disease in survivors of HL, and provides cardiac risk estimates for counseling treated patients, directing their follow-up care, and guiding mediastinal RT planning in newly diagnosed patients.
Radiation-induced valvular disease is the logical consequence of irradiation
- MedicineGeneral thoracic and cardiovascular surgery
- 2007
In the pathological findings, certain rheumatic endocarditis changes such as endocardial reduplication and vascularization were not found in all aortic valves, suggesting radiation-induced cardiac disease will likely become more rare in the future.
Radiation-associated valvular disease.
- MedicineChest
- 1991
A continuum ofValvular disease following radiation that begins with mild asymptomatic valvular thickening and progresses to severe valvULAR fibrosis with hemodynamic compromise requiring surgical intervention is defined.
Radiation Dose-Response Relationship for Risk of Coronary Heart Disease in Survivors of Hodgkin Lymphoma.
- MedicineJournal of clinical oncology : official journal of the American Society of Clinical Oncology
- 2016
The linear radiation dose-response relationship identified can be used to predictCHD risk for future HL patients and survivors and Appropriate early management of CHD risk factors and stimulation of physical activity may reduce CHDrisk in HL survivors.
Mediastinal irradiation: A risk factor for atherosclerosis of the internal thoracic arteries.
- MedicineThe Canadian journal of cardiology
- 1999
A 40-year-old man who required coronary artery bypass grafting for multivessel coronary artery disease 11 years following radiotherapy for Hodgkin's lymphoma is reported, and preoperative angiography showed that the right internal thoracic artery had significant atherosclerosis and was unsuitable as a conduit.