Radiation-induced genomic instability in haemopoietic cells.

  title={Radiation-induced genomic instability in haemopoietic cells.},
  author={Eric G. Wright},
  journal={International journal of radiation biology},
  volume={74 6},
  • Eric G. Wright
  • Published 1998 in International journal of radiation biology
PURPOSE To review studies of radiation-induced genomic instability in haemopoietic cells. MAJOR FINDINGS Studies have demonstrated a high frequency of non-clonal, cytogenetic abnormalities in the clonal descendants of alpha-particle-irradiated (approximately one track per cell) primary murine and human haemopoietic stem cells in vitro. The induction of this phenomenon has a strong dependence on the genetic characteristics of the cells and is transmissible in vivo following transplantation of… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 32 extracted citations

Similar Papers

Loading similar papers…