Radiation-induced epigenetic alterations after low and high LET irradiations.


Epigenetics, including DNA methylation and microRNA (miRNA) expression, could be the missing link in understanding radiation-induced genomic instability (RIGI). This study tests the hypothesis that irradiation induces epigenetic aberrations, which could eventually lead to RIGI, and that the epigenetic aberrations induced by low linear energy transfer (LET… (More)
DOI: 10.1016/j.mrfmmm.2010.12.003