Radiation-induced craniofacial bone growth disturbances.

  title={Radiation-induced craniofacial bone growth disturbances.},
  author={Artur M Gevorgyan and Giorgio Carlo La Scala and Peter C. Neligan and C. Y. Amy Pang and Christopher R. Forrest},
  journal={The Journal of craniofacial surgery},
  volume={18 5},
Multimodality treatment, including radiotherapy, chemotherapy, and surgery, is required for the management of head and neck cancer in pediatric patients. Despite the modern advances in radiation dosing and targeting techniques, the radiation damage to the growing craniofacial skeleton in children remains a significant clinical problem. The first part of this review summarizes the clinical effects of radiotherapy on craniofacial bone growth in children. Experimental evidence on therapeutic… CONTINUE READING

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