Radiation-induced adaptive response is not seen in cell lines showing a bystander effect but is seen in lines showing HRS/IRR response.

@article{Ryan2009RadiationinducedAR,
  title={Radiation-induced adaptive response is not seen in cell lines showing a bystander effect but is seen in lines showing HRS/IRR response.},
  author={Lorna A Ryan and Colin B. Seymour and Michael C. Joiner and Carmel E. Mothersill},
  journal={International journal of radiation biology},
  year={2009},
  volume={85 1},
  pages={87-95}
}
PURPOSE A previous study comparing the bystander effect and low-dose hypersensitivity found that they were inversely correlated. In the current study seven cell lines with established bystander effect and hyper-radiosensitivity/increased radioresistance (HRS/IRR) were further screened for the presence of an adaptive response. MATERIALS AND METHODS Cell survival after exposure to direct radiation with or without a 0.1 Gy priming dose, was determined using the colony forming assay for seven… CONTINUE READING

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