Radiation-induced DNA damage and delayed induced genomic instability

@article{Suzuki2003RadiationinducedDD,
  title={Radiation-induced DNA damage and delayed induced genomic instability},
  author={Keiji Suzuki and Mitsuaki Ojima and Seiji Kodama and Masami Watanabe},
  journal={Oncogene},
  year={2003},
  volume={22},
  pages={6988-6993}
}
Ionizing radiation induces genomic instability, which is transmitted over many generations after irradiation through the progeny of surviving cells. Induced genomic instability is manifested as the expression of the following delayed effects: delayed reproductive death or lethal mutation, chromosomal instability, and mutagenesis. Since induced genomic instability accumulates gene mutations (actually genomic instability is the process whereby gene mutation increases subtle difference) and gross… CONTINUE READING