Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial☆

@inproceedings{Azria2015RadiationinducedCT,
  title={Radiation-induced CD8 T-lymphocyte Apoptosis as a Predictor of Breast Fibrosis After Radiotherapy: Results of the Prospective Multicenter French Trial☆},
  author={David Azria and Olivier Riou and Florence Castan and Tan Dat Nguyen and Karine Peignaux and Claire Lemanski and J. L. Lagrange and Youlia M. Kirova and Eric F. Lartigau and Yazid Belkac{\'e}mi and C{\'e}line Bourgier and Sof{\'i}a Cheverr{\'i}a Rivera and Jean Bourhis and S{\'e}bastien Clippe and Françoise Mornex and C Hennequin and Andrew Kramar and Sophie Gourgou and A Pardo Pelegr{\'i}n and Pascal Fenoglietto and Esat Mahmut Ozsahin},
  booktitle={EBioMedicine},
  year={2015}
}
BACKGROUND Monocentric cohorts suggested that radiation-induced CD8 T-lymphocyte apoptosis (RILA) can predict late toxicity after curative intent radiotherapy (RT). We assessed the role of RILA as a predictor of breast fibrosis (bf +) after adjuvant breast RT in a prospective multicenter trial. METHODS A total of 502 breast-cancer patients (pts) treated by conservative surgery and adjuvant RT were recruited at ten centers. RILA was assessed before RT by flow cytometry. Impact of RILA on bf… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 30 REFERENCES

CD4 and CD8 T-lymphocyte apoptosis can predict radiation-induced late toxicity: a prospective study in 399 patients.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2005
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Does cosmetic outcome from treatment of primary breast cancer influence psychosocial morbidity?

  • European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • 1999
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL

STROGAR - STrengthening the Reporting Of Genetic Association studies in Radiogenomics.

  • Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
  • 2014
VIEW 1 EXCERPT