Radiation hybrid mapping of the zebrafish genome.

  title={Radiation hybrid mapping of the zebrafish genome.},
  author={Neil A Hukriede and Lucille Joly and Michael Tsang and Jennifer Miles and Patricia A. Tellis and Jonathan A. Epstein and W. Bradley Barbazuk and F N Li and Barry H Paw and John H Postlethwait and Thomas J. Hudson and Leonard I. Zon and John D. McPherson and Mario Chevrette and Igor B Dawid and Stephen L. Johnson and Marc Ekker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={96 17},
The zebrafish is an excellent genetic system for the study of vertebrate development and disease. In an effort to provide a rapid and robust tool for zebrafish gene mapping, a panel of radiation hybrids (RH) was produced by fusion of irradiated zebrafish AB9 cells with mouse B78 cells. The overall retention of zebrafish sequences in the 93 RH cell lines that constitute the LN54 panel is 22%. Characterization of the LN54 panel with 849 simple sequence length polymorphism markers, 84 cloned genes… CONTINUE READING
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