Radiation effects on the cytoskeleton of endothelial cells and endothelial monolayer permeability.

@article{Gabry2007RadiationEO,
  title={Radiation effects on the cytoskeleton of endothelial cells and endothelial monolayer permeability.},
  author={Dorota Gabryś and Olga Greco and Gaurang Patel and Kevin M Prise and Gillian M. Tozer and Chryso Kanthou},
  journal={International journal of radiation oncology, biology, physics},
  year={2007},
  volume={69 5},
  pages={1553-62}
}
PURPOSE To investigate the effects of radiation on the endothelial cytoskeleton and endothelial monolayer permeability and to evaluate associated signaling pathways, which could reveal potential mechanisms of known vascular effects of radiation. METHODS AND MATERIALS Cultured endothelial cells were X-ray irradiated, and actin filaments, microtubules, intermediate filaments, and vascular endothelial (VE)-cadherin junctions were examined by immunofluorescence. Permeability was determined by the… CONTINUE READING

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