Radiation abscopal antitumor effect is mediated through p53.

@article{Camphausen2003RadiationAA,
  title={Radiation abscopal antitumor effect is mediated through p53.},
  author={Kevin Camphausen and Marsha A Moses and Cynthia M{\'e}nard and Mary Sproull and Wolf-Dietrich Beecken and Judah Folkman and Michael S O'reilly},
  journal={Cancer research},
  year={2003},
  volume={63 8},
  pages={
          1990-3
        }
}
The observation that radiation treatment to a local area of the body results in an antitumor effect for tumors distant to the radiation site has been termed the "abscopal effect." To understand the mechanism of this unusual phenomenon, we examined whether the effect was mediated through p53, a protein complex up-regulated in irradiated cells. Non-tumor-bearing legs of C57BL/6 (wild-type p53) and p53 null B6.129S2-Trp53(tm1Tyj) mice were irradiated to determine whether an abscopal effect could… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 110 CITATIONS, ESTIMATED 43% COVERAGE

FILTER CITATIONS BY YEAR

2004
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 9 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES