Long-term functional outcomes after treatment for localized prostate cancer
- MJ Resnick, T Koyama, KH Fan, PC Albertsen, M Goodman, AS Hamilton
- N Engl J Med
Secondary malignancy arising following brachytherapy for prostate cancer is rare in medical literature. We present a case of post-brachytherapy soft tissue sarcoma in the pelvis approximately 7 years after 103-P permanent seed implant. The patient developed a large left pelvic mass associated with significant left leg pain. He was not a good candidate for radical surgery, chemotherapy, or re-irradiation. Due to the paucity of high-quality studies, the exact role of prostate brachytherapy in radiationinduced soft tissue sarcoma is still unclear. We seek to review the existing literature on radiation-induced soft tissue sarcoma.