Radiation‐related mortality among offspring of atomic bomb survivors: A half‐century of follow‐up

@article{Izumi2003RadiationrelatedMA,
  title={Radiation‐related mortality among offspring of atomic bomb survivors: A half‐century of follow‐up},
  author={Shizue Izumi and Akihiko Suyama and Kojiro Koyama},
  journal={International Journal of Cancer},
  year={2003},
  volume={107}
}
Our objective was to examine whether parental exposure to atomic bomb radiation has led to increased cancer and/or noncancer mortality rates among the offspring. We studied 41,010 subjects born from May 1946 through December 1984 (i.e., conceived between 1 month and 38 years after the bombings) and surviving for at least 1 year. One or both parents were in Hiroshima or Nagasaki at the time of the bombings and childbirth. We analyzed mortality data from 1946 to 1999 using the Japanese family… 
Cancer incidence in children and young adults did not increase relative to parental exposure to atomic bombs
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Cancer incidence was no higher for subjects with exposed parents than for the reference subjects, nor did the incidence rates increase with increasing dose, and the adjusted risk ratio for all cancer was 0.97; because of the small number of cases, however, one cannot exclude an increase in cancer incidence at this time.
Japanese Legacy Cohorts: The Life Span Study Atomic Bomb Survivor Cohort and Survivors’ Offspring
TLDR
In children of survivors, no increased risks due to parental exposure to radiation have been observed for malignancies or other diseases, but investigations are continuing, as these cohorts are still relatively young, and epidemiological studies have observed increased radiation risks for malignant diseases among survivors.
Epidemiological research on radiation-induced cancer in atomic bomb survivors
  • K. Ozasa
  • Medicine
    Journal of radiation research
  • 2016
The late effects of exposure to atomic bomb radiation on cancer occurrence have been evaluated by epidemiological studies on three cohorts: a cohort of atomic bomb survivors (Life Span Study; LSS),
The Offspring of Atomic Bomb Survivors: Cancer and Non-Cancer Mortality and Cancer Incidence
TLDR
There is no evidence of a significant association between parental gonadal doses and F1 mortality or cancer incidence, according to the long-term follow-up of the children of the atomic bomb survivors.
Genetic effects of radiation in atomic-bomb survivors and their children: past, present and future.
TLDR
A clinical program is underway to establish the frequency of adult-onset multi-factorial diseases (diabetes mellitus, high blood pressure, and cardiovascular disease etc) in the offspring and the complementary kinds of data that will emerge from this three-pronged approach promise to shed light on health effects inThe offspring of radiation-exposed people.
Radiation risk of individual multifactorial diseases in offspring of the atomic-bomb survivors: a clinical health study.
  • Y. Tatsukawa, J. Cologne, R. Shore
  • Medicine
    Journal of radiological protection : official journal of the Society for Radiological Protection
  • 2013
TLDR
There is no evidence that paternal or maternal A-bomb radiation dose, or the sum of their doses, was associated with an increased risk of any multifactorial diseases in either male or female offspring.
Long-term Radiation-Related Health Effects in a Unique Human Population: Lessons Learned from the Atomic Bomb Survivors of Hiroshima and Nagasaki
TLDR
This article reviews risk estimates for radiation-related health effects in survivors of the atomic bombings of Hiroshima and Nagasaki and in their children and summarizes what has been learned from this historic and unique study.
Impact on the Japanese Atomic Bomb Survivors of Radiation Received From the Bombs
TLDR
The total impact of the radiation from the bombs on the survivors is summarized from both an individual perspective (both age-specific and integrated lifetime risk, along with a measure of life expectancy that describes how the risk affects the individual given age at exposure) and a group perspective (estimated numbers of excess occurrences in the cohort).
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