Radial immunodiffusion assay of apolipoprotein B in blood dried on filter paper--a potential screening method for familial type II hypercholesterolaemia.

@article{Dudman1985RadialIA,
  title={Radial immunodiffusion assay of apolipoprotein B in blood dried on filter paper--a potential screening method for familial type II hypercholesterolaemia.},
  author={Nicholas Peter Dudman and Barbara L Blades and David Emil Leon Wilcken and J M Aitken},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1985},
  volume={149 2-3},
  pages={117-27}
}
In the search for an effective neonatal screening programme for familial type II hypercholesterolaemia, we have developed and validated a radial immunodiffusion assay for measuring, in dried blood spots, the concentration of apolipoprotein B. The method has advantages over previously described methods, being cheaper, more robust, and suitable for partial automation. In 34 adults there was a close linear relationship between capillary and venous blood spot apolipoprotein B concentrations (r = 0… CONTINUE READING

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