Radial glia phenotype: origin, regulation, and transdifferentiation.

  title={Radial glia phenotype: origin, regulation, and transdifferentiation.},
  author={G Chanas-Sacr{\'e} and Bernard Rogister and Gustave Moonen and Pierre Leprince},
  journal={Journal of neuroscience research},
  volume={61 4},
Radial glial cells play a major guidance role for migrating neurons during central nervous system (CNS) histogenesis but also play many other crucial roles in early brain development. Being among the earliest cells to differentiate in the early CNS, they provide support for neuronal migration during embryonic brain development; provide instructive and neurotrophic signals required for the survival, proliferation, and differentiation of neurons; and may be multipotential progenitor cells that… CONTINUE READING


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Structure/function studies of lin-12/Notch proteins.

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