Radial, spiral and reverberating waves of spreading depolarization occur in the gyrencephalic brain

@article{Santos2014RadialSA,
  title={Radial, spiral and reverberating waves of spreading depolarization occur in the gyrencephalic brain},
  author={E. Santos and M. Sch{\"o}ll and R. S{\'a}nchez-Porras and M. Dahlem and H. Silos and A. Unterberg and H. Dickhaus and O. Sakowitz},
  journal={NeuroImage},
  year={2014},
  volume={99},
  pages={244-255}
}
OBJECTIVES The detection of the hemodynamic and propagation patterns of spreading depolarizations (SDs) in the gyrencephalic brain using intrinsic optical signal imaging (IOS). METHODS The convexity of the brain surface was surgically exposed in fourteen male swine. Within the boundaries of this window, brains were immersed and preconditioned with an elevated K(+) concentration (7 mmol/l) in the standard Ringer lactate solution for 30-40 min. SDs were triggered using 3-5 μl of 1 mol/l KCl… Expand
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