Rad54, the motor of homologous recombination.

  title={Rad54, the motor of homologous recombination.},
  author={A. V. Mazin and Olga M. Mazina and Dmitry V. Bugreev and Matthew J. Rossi},
  journal={DNA repair},
  volume={9 3},
Homologous recombination (HR) performs crucial functions including DNA repair, segregation of homologous chromosomes, propagation of genetic diversity, and maintenance of telomeres. HR is responsible for the repair of DNA double-strand breaks and DNA interstrand cross-links. The process of HR is initiated at the site of DNA breaks and gaps and involves a search for homologous sequences promoted by Rad51 and auxiliary proteins followed by the subsequent invasion of broken DNA ends into the… CONTINUE READING


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Publications referenced by this paper.
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The architecture of the human Rad54-DNA complex provides evidence for protein translocation along DNA.

Proceedings of the National Academy of Sciences of the United States of America • 2001
View 4 Excerpts
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Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae.

Microbiology and molecular biology reviews : MMBR • 1999
View 4 Excerpts
Highly Influenced

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