Racial disparity of epidermal growth factor receptor expression in prostate cancer.

@article{Shuch2004RacialDO,
  title={Racial disparity of epidermal growth factor receptor expression in prostate cancer.},
  author={Brian Shuch and M. Mikhail and Jaya M. Satagopan and Peng Ng Ang Noi Lee and Herman Yee and Caroline Y Chang and Carlos Cordon-Cardo and Samir S. Taneja and Iman Osman},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2004},
  volume={22 23},
  pages={4725-9}
}
PURPOSE The epidermal growth factor receptor (EGFR) plays a critical role in prostate cancer (PC) signal transduction and is the target of a novel class of anticancer agents. Despite recent reports of interethnic variation in response to EGFR inhibitors, limited information exists regarding differences in expression of EGFR in PC patients. This has therapeutic relevance because a better understanding of the molecular basis underlying the ethnic variability will help in the design of… CONTINUE READING

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