Racial differences in the distribution of systemic sclerosis-related serum antinuclear antibodies.

@article{Kuwana1994RacialDI,
  title={Racial differences in the distribution of systemic sclerosis-related serum antinuclear antibodies.},
  author={Masataka Kuwana and Yutaka Okano and Junichi Kaburaki and Tadashi Tojo and Thomas A Jr Medsger},
  journal={Arthritis and rheumatism},
  year={1994},
  volume={37 6},
  pages={902-6}
}
OBJECTIVE To determine racial differences in the frequencies of systemic sclerosis (SSc)-related serum antinuclear antibodies (ANA). METHODS We tested serum samples from 275 Japanese, 416 North American Caucasian, and 24 North American black SSc patients for 8 SSc-related serum ANA, using indirect immunofluorescence, double immunodiffusion, and radioimmunoprecipitation assays. RESULTS In comparing the 3 racial groups, we found that anti-U1 RNP, anti-RNA polymerase I, II, and III, and anti… CONTINUE READING

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