Racial Differences in Paraoxonase-1 (PON1): A Factor in the Health of Southerners?

@inproceedings{Davis2009RacialDI,
  title={Racial Differences in Paraoxonase-1 (PON1): A Factor in the Health of Southerners?},
  author={Kimberly A. Davis and J Allen Crow and Howard Wayne Chambers and Edward Caldwell Meek and Janice Elaine Chambers},
  booktitle={Environmental health perspectives},
  year={2009}
}
BACKGROUND The southern United States (excluding Florida) has the highest age-adjusted rate of cardiovascular disease (CVD) in the country, with African Americans having a higher prevalence of CVD than Caucasians. Paraoxonase-1 (PON1), an enzyme associated with high-density lipoprotein particles, participates both in the hydrolysis of oxidized lipids (thus protecting against atherosclerosis) and in the hydrolysis of organophosphates. Higher paraoxonase activity has been associated with lower… CONTINUE READING