Race influences the safety and efficacy of spironolactone in severe heart failure.

Abstract

BACKGROUND The incidence of hyperkalemia caused by mineralocorticoid receptor antagonists may vary by race, but whether race influences efficacy of mineralocorticoid receptor antagonists in heart failure (HF) is unknown. METHODS AND RESULTS We assessed hyperkalemia and outcomes in African Americans (AAs; n=120) and non-AAs (n=1543; white 93%) with New… (More)
DOI: 10.1161/CIRCHEARTFAILURE.113.000530

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