Race-based therapeutics.
@article{Bloche2004RacebasedT, title={Race-based therapeutics.}, author={M. Gregg Bloche}, journal={The New England journal of medicine}, year={2004}, volume={351 20}, pages={ 2035-7 } }
Are we moving into a new era of race-based therapeutics? Dr. M. Gregg Bloche asserts that greater awareness that race is at best a placeholder for other predispositions, and not a biologic verity, would be a first step.
145 Citations
Pharmacogenomics: Reflecting on the Old and New Social, Ethical and Policy Issues in Postgenomics Medicine
- Medicine
- 2010
Whenever a new form of biotechnology is introduced, there is often uncertainty around its intended and unintended impacts on science, medicine and society. Past experiences with genetically modified o
Beyond Best Practices: Strict Scrutiny as a Regulatory Model for Race-Specific Medicines
- Political ScienceJournal of Law, Medicine & Ethics
- 2008
It may be useful for the FDA to turn to an area with experience negotiating such dilemmas — constitutional law — and its approach — strict scrutiny — to help guide when and under which circumstances government should give effect to racial categories in biomedicine.
The race to prescribe: Drug for African Americans may debut amid debate
- Medicine
- 2005
Identifying such inequalities is one step toward helping each population get appropriate medical care. Sometimes, that requires making the same tests and treatments available across the board, but it…
The A-HeFT Trial: More Questions than Answers
- Medicine, Biology
- 2005
This continuing feature will update readers on recent developments in cardiovascular pharmacotherapy, as well as encouraging pharmacists to keep current with developments in drug therapy.
Race, Money and Medicines
- MedicineThe Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics
- 2006
This essay argues that the authors should start with a presumption against racial categories in medicine, but permit their use when it might prolong lives or meaningfully improve health, and follow-up inquiry into the factors that underlie race-correlated clinical differences is important.
Race‐based therapeutics A discussion surrounding heart failure trials
- MedicineJAAPA : official journal of the American Academy of Physician Assistants
- 2007
Alarmingly, blacks comprise the largest percentage of those with these forms of CVD, and they die disproportionately compared to other racial groups, and the differences in response to drug therapies that are garnering extra attention and that have provoked a discussion regarding race-based therapies.
Racial medicine: here to stay?
- Medicine
- 2006
Now that the human genome sequence is complete, several follow‐up genomic projects, most notably the HapMap initiative to identify and catalogue haplotypes, are focusing on identifying such genetic variants, but it is not yet clear whether this knowledge will lead to personalized medicine.
BiDil in the Clinic: An Interdisciplinary Investigation of Physicians’ Prescription Patterns of a Race-Based Therapy
- MedicineAJOB empirical bioethics
- 2014
Overall, physicians prescribe and are willing to prescribe BiDil more to black patients than to white patients, and physicians’ lack of awareness about the controversial scientific status of A-HeFT suggests the need for more efficient ways to convey scientific information about BiDIL to clinicians.
Pharmacogenetics and geographical ancestry: implications for drug development and global health
- BiologyNature Reviews Genetics
- 2005
It is argued that, for the foreseeable future, medicine should focus not on boutique 'personalized' medicine, but on carefully defined differences between populations and ethical ways of using emerging genomics knowledge to develop drugs and improve health.
Legal Regulation of the Use of Race in Medical Research
- LawThe Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics
- 2006
Whether the use of race in various types of research is presently permitted under federal law and the federal constitution and whether federal policies that encourage theUse of race ought to be abandoned is discussed.
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