Race and genomics.

@article{Cooper2003RaceAG,
  title={Race and genomics.},
  author={Richard S. Cooper and Jay S. Kaufman and Ryk H. Ward},
  journal={The New England journal of medicine},
  year={2003},
  volume={348 12},
  pages={
          1166-70
        }
}
These two articles present contrasting views of the usefulness of the concept of race in biomedical research and clinical practice. 

Figures from this paper

Race, genomics, and health care.
  • F. Lagay
  • Medicine
    The virtual mentor : VM
  • 2003
Medical ethicists have discussed the use of race classification in determining disease prevalence and the response of specific ethnic groups to different medications. Virtual Mentor is a monthly
Race, ethnic group, and clinical research
TLDR
Implications of incorporating race and ethnicity into trials go beyond ethical issues and beyond, according to research published in the Journal of Human Rights and Experimental Medicine.
Ancestry and disease in the age of genomic medicine.
TLDR
Genomic analyses indicate that although humans have a common origin and most genetic variation is shared, there are some differences among groups of humans that may be harnessed to improve human well-being.
Personalizing medicine: beyond race.
TLDR
Instead of using race as a shorthand for factors that directly influence health, researchers should investigate those factors themselves, according to a report in the British Journal of Sports Medicine.
Are medical and nonmedical uses of large-scale genomic markers conflating genetics and 'race'?
“...with each birth and each death we alter the genetic attributes of human populations and drawing a line around an ephemeral entity like a human race is an exercise in futility and idiocy.” —Pat
Inclusiveness and ethical considerations for observational, translational, and clinical cancer health disparity research
Although general trends in cancer outcomes are improving, racial/ethnic disparities in patient outcomes continue to widen, suggesting disparity‐related shortcomings in cancer research designs.
Ethnicity, Ancestry, and Race in Molecular Epidemiologic Research
The concepts of ethnicity, ancestry, and race are widely used in molecular epidemiologic research, often based on the assumption that these correlate (however roughly) with increased genetic
"Race" and biomedical research: An educational perspective.
TLDR
All humans belong to the same species: Homo sapiens, however, they vary significantly in terms of individuality, age, sex, and population group.
The meaning of race in healthcare and research--part 2. Current controversies and emerging research.
  • C. Tashiro
  • Medicine, Political Science
    Pediatric nursing
  • 2005
TLDR
Pediatric nurses must examine the literature on race, as well as their own assumptions, and be clear about when and why the authors use racial categories and what they really mean.
...
...

References

SHOWING 1-10 OF 32 REFERENCES
Categorization of humans in biomedical research: genes, race and disease
TLDR
An epidemiologic perspective on the issue of human categorization in biomedical and genetic research that strongly supports the continued use of self-identified race and ethnicity is provided.
Medicine and the racial divide.
TLDR
Two Sounding Board articles in this issue of the Journal are the most recent contributions to the debate over whether race — defined broadly as the sharing of a common ancestry — should be considered by those who study disease and patients' responses to treatment.
The role of race in heart failure therapy
  • C. Yancy
  • Medicine
    Current cardiology reports
  • 2002
Heart failure in blacks is a unique malady characterized by a different natural history, more worrisome prognosis, and potential variances in the response to current medical therapy for heart
Adrenergic-receptor polymorphisms and heart failure.
Congestive heart failure is the eventual outcome of diverse myocardial insults, including postischemic remodeling, primary cardiomyopathies, and infections.1 Even for specific forms of myocardial i...
The prevalence of hypertension in seven populations of west African origin.
TLDR
The findings demonstrate the determining role of social conditions in the evolution of hypertension risk in these populations of West African origin, and show that environmental factors varied consistently with disease prevalence across regions.
The Structure of Haplotype Blocks in the Human Genome
TLDR
It is shown that the human genome can be parsed objectively into haplotype blocks: sizable regions over which there is little evidence for historical recombination and within which only a few common haplotypes are observed.
Haplotype Variation and Linkage Disequilibrium in 313 Human Genes
TLDR
Pairs of SNPs exhibited variability in the degree of linkage disequilibrium that was a function of their location within a gene, distance from each other, population distribution, and population frequency.
Blood pressure variation in blacks: genetic factors.
TLDR
A strong genetic component for the physiology of "salt sensitivity" is suggested, and Phenotypes that are indicative of this sensitivity are more common in African Americans than in Americans of European descent and in hypertensive African American compared with normotensive African Americans.
...
...