Rabies virus neuritic paralysis: immunopathogenesis of nonfatal paralytic rabies.

@article{Weiland1992RabiesVN,
  title={Rabies virus neuritic paralysis: immunopathogenesis of nonfatal paralytic rabies.},
  author={Frank Weiland and James Hilton Cox and Salome Meyer and Erwin Dahme and Matthias Johannes Reddehase},
  journal={Journal of virology},
  year={1992},
  volume={66 8},
  pages={5096-9}
}
Two pathogenetically distinct disease manifestations are distinguished in a murine model of primary rabies virus infection with the Evelyn-Rokitnicky-Abelseth strain, rabies virus neuritic paralysis (RVNP) and fatal encephalopathogenic rabies. RVNP develops with high incidence in immunocompetent mice after intraplantar infection as a flaccid paralysis restricted to the infected limb. The histopathologic correlate of this monoplegia is a degeneration of the myelinated motor neurons of the… CONTINUE READING

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