Rabies virus is not cytolytic for rat spinal motoneurons in vitro

@article{Guigoni2002RabiesVI,
  title={Rabies virus is not cytolytic for rat spinal motoneurons in vitro},
  author={C{\'e}line Guigoni and Patrice Coulon},
  journal={Journal of NeuroVirology},
  year={2002},
  volume={8},
  pages={306-317}
}
Cultures of purified rat embryonic spinal cord motoneurons were used to investigate the capacity of the neurons to survive rabies virus infection in vitro. In crude primary spinal cord cultures, neurons did not survive more than 2 days after rabies virus infection with the fixed strain Challenge Virus Standard. In contrast, virus-infected purified motoneurons resisted cytolysis for at least 7 days, as also did infected motoneurons treated with conditioned medium sampled from rabies virus… CONTINUE READING
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