Rabeprazole is effective in treating laryngopharyngeal reflux in a randomized placebo-controlled trial.

@article{Lam2010RabeprazoleIE,
  title={Rabeprazole is effective in treating laryngopharyngeal reflux in a randomized placebo-controlled trial.},
  author={Paul Kin-Yip Lam and Manwa L. Ng and Ting Kin Cheung and Birgitta Yee Hang Wong and V P Y Tan and Daniel Yee Tak Fong and William Ignace Wei and Benjamin Chun-yu Wong},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2010},
  volume={8 9},
  pages={770-6}
}
BACKGROUND & AIMS There is controversy about the efficacy of treating patients with laryngopharyngeal reflux (LPR) using proton pump inhibitors (PPIs). We assessed the effects of high doses of the PPI rabeprazole in patients with LPR. METHODS Patients with LPR symptoms were assigned randomly to receive rabeprazole (20 mg, twice daily, n = 42) or placebo (n = 40) for 12 weeks. All patients completed symptom questionnaires; these provided demographic information and the reflux symptom index… CONTINUE READING