Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane.

@article{Naslavsky2004Rabenosyn5AE,
  title={Rabenosyn-5 and EHD1 interact and sequentially regulate protein recycling to the plasma membrane.},
  author={Naava Naslavsky and Markus B{\"o}hm and Peter S. Backlund and Steve Caplan},
  journal={Molecular biology of the cell},
  year={2004},
  volume={15 5},
  pages={
          2410-22
        }
}
EHD1 has been implicated in the recycling of internalized proteins to the plasma membrane. However, the mechanism by which EHD1 mediates recycling and its relationship to Rab-family-controlled events has yet to be established. To investigate further the mode of EHD1 action, we sought to identify novel interacting partners. GST-EHD1 was used as bait to isolate a approximately 120-kDa species from bovine and murine brain cytosol, which was identified by mass spectrometry as the divalent Rab4/Rab5… CONTINUE READING