Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps.

@article{Chittum1998RabbitBI,
  title={Rabbit beta-globin is extended beyond its UGA stop codon by multiple suppressions and translational reading gaps.},
  author={Harold S. Chittum and William S. Lane and Bradley A. Carlson and Peter P. Roller and F D Lung and Byeong Jae Lee and Dolph Lee Hatfield},
  journal={Biochemistry},
  year={1998},
  volume={37 31},
  pages={10866-70}
}
Translational reading gaps occur when genetic information encoded in mRNA is not translated during the normal course of protein synthesis. This phenomenon has been observed thus far only in prokaryotes and is a mechanism for extending the reading frame by circumventing the normal stop codon. Reading frames of proteins may also be extended by suppression of the stop codon mediated by a suppressor tRNA. The rabbit beta-globin read-through protein, the only known, naturally occurring read-through… CONTINUE READING
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