Rab35 Regulates an Endocytic Recycling Pathway Essential for the Terminal Steps of Cytokinesis

@article{Kouranti2006Rab35RA,
  title={Rab35 Regulates an Endocytic Recycling Pathway Essential for the Terminal Steps of Cytokinesis},
  author={I. Kouranti and M. Sachse and N. Arouche and B. Goud and A. Echard},
  journal={Current Biology},
  year={2006},
  volume={16},
  pages={1719-1725}
}
Cytokinesis is the final step of cell division and leads to the physical separation of the daughter cells. After the ingression of a cleavage membrane furrow that pinches the mother cell, future daughter cells spend much of the cytokinesis phase connected by an intercellular bridge. Rab proteins are major regulators of intracellular transport in eukaryotes, and here, we report an essential role for human Rab35 in both the stability of the bridge and its final abscission. We find that Rab35… Expand
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