Rab27a Was Identified as a Prognostic Biomaker by mRNA Profiling, Correlated with Malignant Progression and Subtype Preference in Gliomas

@inproceedings{Wang2014Rab27aWI,
  title={Rab27a Was Identified as a Prognostic Biomaker by mRNA Profiling, Correlated with Malignant Progression and Subtype Preference in Gliomas},
  author={Hongjun Wang and Yan Zhao and Chuan-bao Zhang and Mingyang Li and Chuanlu Jiang and Yongli Li},
  booktitle={PloS one},
  year={2014}
}
PURPOSE Rab27a belongs to the Rab small GTPase superfamily. The protein is membrane-bound and may be involved in protein transport and small GTPase-mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. However, the prognostic and molecular features of gliomas with Rab27a expression are still unclear. EXPERIMENTAL DESIGN We used a whole-genome mRNA expression microarray dataset of 220 glioma samples from the Chinese Glioma Genome Atlas (CGGA… CONTINUE READING

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