Rab11-like GTPase associates with and regulates the structure and function of the contractile vacuole system in dictyostelium.

@article{Harris2001Rab11likeGA,
  title={Rab11-like GTPase associates with and regulates the structure and function of the contractile vacuole system in dictyostelium.},
  author={Edward Harris and Kunito Yoshida and James Cardelli and John G Bush},
  journal={Journal of cell science},
  year={2001},
  volume={114 Pt 16},
  pages={3035-45}
}
Screening of a cDNA library revealed the existence of a Dictyostelium cDNA encoding a protein 80% identical at the amino acid level to mammalian Rab11. Subcellular fractionation and immunofluorescence studies revealed that DdRab11 was exclusively associated with the ATPase proton pump-rich contractile vacuole membrane system, consisting of a reticular network and bladder-like vacuoles. Video microscopy of cells expressing GFP-DdRab11 revealed that this Rab was associated with contractile… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Characterization of Iysosomes isolated from Dictyosteliurn discoideurn by magnetic fractionation . 1

  • A. Rupper, J. Cardelli
  • BioI . Chern .
  • 2001

Proton pumps populate the contractile vacuoles of Dictyosteliurn discoideurn . 1

  • M. Maniak
  • Cell BioI .
  • 2001

DdRabll redistributes to apical secretory canaliculus during stimulation of gastric parietal cells

  • D. Cox, D. Lee, B. Dale, J. Calafat, S. Greenberg
  • Am . 1 . Physiol .
  • 2000

Cloning and characterization of a Dictyosteliurn gene encoding a small GTPase of the Rab 11 family . 1

  • D. Gabriel, u. Hacker, +4 authors G. Gerisch
  • Cell Biochern .
  • 1999

Similar Papers

Loading similar papers…