Rab11-FIP2 influences multiple components of the endosomal system in polarized MDCK cells.

@article{Ducharme2011Rab11FIP2IM,
  title={Rab11-FIP2 influences multiple components of the endosomal system in polarized MDCK cells.},
  author={Nicole Ducharme and Amy-Joan L. Ham and Lynne A. Lapierre and James R Goldenring},
  journal={Cellular logistics},
  year={2011},
  volume={1 2},
  pages={
          57-68
        }
}
The Rab11 Family Interacting Proteins (Rab11-FIPs) are hypothesized to regulate sequential steps in the apical recycling and transcytotic pathways of polarized epithelial cells. Previous studies have suggested that Rab11-FIP proteins assemble into multi-protein complexes regulating plasma membrane recycling. Rab11-FIP2 interacts with both myosin Vb and Rab11. Recent investigations have noted that that Rab11-FIP2 mutants [Rab11-FIP2(129-512), also designated Rab11-FIP2(ΔC2) and Rab11-FIP2(S229A… CONTINUE READING
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